Chromosomal architecture

Author: mjzo

August undefined, 2024

WebFeb 5, 2016 · We applied a combination of whole-genome chromosome conformation capture (Hi-C), fluorescence in situ hybridization, and in silico modeling methods … WebSep 30, 2024 · Finally, lncRNAs serve key roles in mediating chromosomal architecture (for review see ), as illustrated by one of the best characterized lncRNAs, XIST, which regulates the compaction of the inactive X chromosome by creating one compact mega domain and preventing TAD formation. The interplay of these factors gives dynamicity to …

Reorganization of chromosome architecture in replicative …

WebNational Center for Biotechnology Information WebEditors: Malgorzata Kloc, Jacek Z. Kubiak. Examines effects of changes in nuclear, chromosomal and genomic architecture in the cell. Addresses implications of such changes for cell development and maturation. Also … is she asleep

Regulation and dysregulation of spatial chromatin structure

WebApr 7, 2024 · Definition. …. A histone is a protein that provides structural support for a chromosome. Each chromosome contains a long molecule of DNA, which must fit into the cell nucleus. To do that, the DNA wraps … WebThe focus now is on proven practices that lead to scale and improved returns. In the emerging world of Ecosystem 2.0, data are the holy grail, the breakdown of sector … WebSep 4, 2014 · How chromosomal architecture is connected to the epigenome is not well understood. We show that chromosomal architecture of Arabidopsis is tightly linked to the epigenetic state. Furthermore, we show how physical constraints, such as nuclear size, correlate with the folding principles of chromatin. is she a singer

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Genomic Instability: The Driving Force behind Refractory/Relapsing ...

WebChromosomal Architecture of Arabidopsis and its Implication in Transposon Intergration: Organism: Arabidopsis thaliana: Experiment type: Other: Summary: Efficient storing and readout of genetic information is not only dependent on tight epigenetic regulation but also on the spatial organization and folding of chromosomes. Although the epigenome ... Web1 day ago · The field of genome architecture has experienced a spectacular advance over the last decades. This progress has been driven by concomitant technological developments (Table 1).On one side, the advent of chromosome conformation capture (3C) 1 and related techniques (high-throughput chromosome conformation capture [Hi-C], genome … ieee conference id numberWebFeb 3, 2024 · In previous studies, genome in situ hybridization (GISH) and Hi-C data showed that the chromosomes of the same subgenome are closer in space [58, 59]. In cotton, the ratio of chromosomal interactions in the At subgenome is higher than in the Dt subgenome, and some genes with biased expression are related to differential chromatin … ieee computing

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Chromosomal architecture

GSDB: a database of 3D chromosome and genome structures …

WebNov 24, 2013 · Employing circular chromosome conformation capture, this study describes chromosomal architecture in Arabidopsis nuclei from a genome-wide perspective. … WebFeb 4, 2024 · We reveal that chromosomes of Sulfolobus archaea are organized into CID-like topological domains in addition to previously described larger A/B compartment-type …

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WebAug 27, 2024 · We provide an overview of the fundamental properties that shape the chromosome as a structured yet dynamic macromolecule. These fundamental properties are then considered in the context of the... WebSep 1, 2024 · Chromosomal Conformation Capture Comparison For the investigation of any relation between DNA-DNA interaction frequencies and correlation of pairwise expression of genomic positions processed data …

WebMay 11, 2024 · As with any evolutionary change of state, chromosomal reorganisations that originate in the germ line before meiosis (proliferating primordial germ cells, spermatogonia and oogonia), during... WebWe have carried out a retrospective study of chromosome anomalies associated with increased nuchal translucency (NT) in order to compare yield rates of karyotype, chromosome microarray analysis (CMA), and non-invasive prenatal testing (NIPT) in this condition. Presenting with increased NT or cystic hygroma ≥3.5 mm as an isolated …

WebRole of chromosomal architecture in germinal center B cells and lymphomagenesis Chromosomal conformation is now recognized as a key feature in the development of a robust humoral immune response. Several examples from the literature show that dysregulation of chromosomal architecture may be a foundational event during … WebApr 24, 2024 · Gene regulatory network reconstruction incorporating 3D chromosomal architecture reveals key transcription factors and DNA elements driving neural lineage …

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WebApr 1, 2024 · The role of Polycomb group proteins in chromosomal architecture. Striking features of Arabidopsis chromosomal architecture termed ‘positive strips’ [25 •] are characterized by excessive 3D contacts to other genomic regions. This could indicate that regions corresponding to positive strips show decreased compaction and, thus, higher … is she a scrabble wordWebJun 5, 2013 · The 3D nuclear architecture is closely related to cellular functions and chromosomes are organized in distinct territories [ 8, 9 ]. Formal proof of these chromosome territories came from the identification of regular and inverted chromosomal architecture in rod cells associated with diurnal and nocturnal vision, respectively, in … is she a subject or verbWebNov 6, 2024 · Extensive studies are currently devoted to understanding the three-dimensional (3D) architecture of genomes, including the formation and function of chromatin loops, topologically associated domains (TADs) and transcriptional activity-based A and B compartments. ieee conference in chennaiWebOct 29, 2024 · Immunolocalization studies to visualize the distribution of proteins on meiotic chromosomes have become an integral part of studies on meiosis in the model organism Arabidopsis thaliana. These techniques have been used to visualize a wide range of meiotic proteins involved in different aspects of meiosis, including sister chromatid cohesion, … ieee conference in bangalore 2022WebMar 1, 2024 · Overall, it is now clear that inter-chromosomal chromatin architecture is not just restricted to active genes in more or less defined nuclear subcompartments or … is sheat a wordWebNov 30, 2015 · How the same DNA sequences can function in the three-dimensional architecture of interphase nucleus, fold in the very compact structure of metaphase chromosomes and go precisely back to the … ieee conference in indiaWebNov 30, 2015 · Chromosomal bands are, however, only one facet of a wider mystery which concerns chromosome architecture: how the same DNA sequences allow configurations as different as those of interphase … ieee conference id