WebThis work demonstrates that Rap2C is a new member of the Rap2 subfamily of proteins, able to bind guanine nucleotides with peculiar properties, and differently expressed by … WebNov 6, 2024 · microRNA-195 Promotes Small Cell Lung Cancer Cell Apoptosis via Inhibiting Rap2C Protein-Dependent MAPK Signal Transduction. Tong J, et al. Technol Cancer …
Pathway Commons: A Resource for Biological Pathway Analysis
WebTogether, Raf, MEK, and the ERKs make up a three-tiered kinase signaling pathway called a mitogen-activated protein kinase (MAPK) cascade.(A mitogen is a signal that causes cells to undergo mitosis, or divide.)Because they play a central role in promoting cell division, the genes encoding the growth factor receptor, Raf, and c-Myc are all proto-oncogenes, … WebMar 21, 2024 · Complete information for RAP2C gene (Protein Coding), RAP2C, Member Of RAS Oncogene Family, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards - The Human Gene Compendium. ... Gene Ontology (GO) - … ACE2 (Angiotensin Converting Enzyme 2) is a Protein Coding gene. Diseases … Complete information for KRAS gene (Protein Coding), KRAS Proto … NF1 (Neurofibromin 1) is a Protein Coding gene. Diseases associated with NF1 … ACE (Angiotensin I Converting Enzyme) is a Protein Coding gene. Diseases … oratane pills side effects
Ras‑related protein Rap2c promotes the migration and …
WebAdenomatous polyposis coli (APC) also known as deleted in polyposis 2.5 (DP2.5) is a protein that in humans is encoded by the APC gene. The APC protein is a negative regulator that controls beta-catenin concentrations and interacts with E-cadherin, which are involved in cell adhesion.Mutations in the APC gene may result in colorectal cancer.. … WebApr 20, 2007 · The Ras family regulates a wide variety of cellular functions that include cell growth, differentiation, and apoptosis. In this study, we identified a novel human gene named RAP2C, isolated from human testis cDNA library, and mapped to Xq26.2 by searching the UCSC genomic database. The RAP2C cDNA contains an open reading … WebFurthermore, miRNA195 prohibited the activation of MAPK signaling pathway by down-regulating Rap2C. These consequences indicated that miRNA-195 promotes the apoptosis and inhibits the proliferation of small cell lung cancer (SCLC) cells via inhibiting Rap2C protein-dependent MAPK signal transduction. oratane south africa